Orbital Frontal Cortex Projections to Secondary Motor Cortex Mediate Exploitation of Learned Rules
نویسندگان
چکیده
منابع مشابه
Secondary Motor Cortex: Where 'Sensory' Meets 'Motor' in the Rodent Frontal Cortex.
In rodents, the medial aspect of the secondary motor cortex (M2) is known by other names, including medial agranular cortex (AGm), medial precentral cortex (PrCm), and frontal orienting field (FOF). As a subdivision of the medial prefrontal cortex (mPFC), M2 can be defined by a distinct set of afferent and efferent connections, microstimulation responses, and lesion outcomes. However, the behav...
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The primary motor cortex (M1) of the rat contains dopaminergic terminals. The origin of this dopaminergic projection and its functional role for movement are obscure. Other areas of cortex receive dopaminergic projections from the ventral tegmental area (VTA) of the midbrain, and these projections are involved in learning phenomena. We therefore hypothesized that M1 receives a dopaminergic proj...
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Recent anatomic and functional data radically changed our ideas about the organization of the motor cortex in primates. Contrary to the classic view, the motor cortex does not consist of two main areas, primary and supplementary motor areas, but of a mosaic of cortical areas with specific connections and functional properties.
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BACKGROUND Postmortem studies have documented abnormalities in the medial orbital frontal cortex in depressed patients. In this study we evaluated whether atrophy of this region can be identified in older depressed patients using magnetic resonance imaging. METHODS Twenty elderly patients meeting DSM-IV criteria for major depression and 20 matched control subjects were studied. The orbital fr...
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Fetal frontal cortex from 18-d-old embryonic rat brain was transplanted into cavities of juvenile host motor/sensory cortex. Two to seven months later, sections were reacted for NADPH-diaphorase (NADPH-d) enzyme histochemistry. NADPH-d-positive neurons survived in 11 of 13 grafts. All but one of the transplants had reduced numbers of these neurons, although in 3 transplants the reductions were ...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2018
ISSN: 2045-2322
DOI: 10.1038/s41598-018-29285-x